Expresión de búsqueda: CYTOCHROME P-450 CYP3A 
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Descriptor Inglés:   Cytochrome P-450 CYP3A 
Descriptor Español:   Citocromo P-450 CYP3A 
Descriptor Portugués:   Citocromo P-450 CYP3A 
Sinónimos Inglés:   3A5, Cytochrome P450
6-alpha-Monooxygenase, Taurochenodeoxycholate
CYP3A
CYP3A4
CYP3A5
Cytochrome P 450 CYP3A
Cytochrome P 450 CYP3A4
Cytochrome P 450 CYP3A5
Cytochrome P 450IIIA
Cytochrome P-450 CYP3A4
Cytochrome P-450 CYP3A5
Cytochrome P-450IIIA
Cytochrome P450 3A
Cytochrome P450 3A4
Cytochrome P450 3A5
Erythromycin N Demethylase
Erythromycin N-Demethylase
N-Demethylase, Erythromycin
P-450 CYP3A, Cytochrome
P-450 CYP3A4, Cytochrome
P-450 CYP3A5, Cytochrome
P-450IIIA, Cytochrome
P450 3A, Cytochrome
P450 3A5, Cytochrome
Taurochenodeoxycholate 6 alpha Monooxygenase
Taurochenodeoxycholate 6-alpha-Monooxygenase  
Categoría:   D08.244.453.860.500
D08.811.682.662.582.353
D08.811.682.690.708.170.495.500
D12.776.422.220.453.860.500
Definición Inglés:   A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN. 
Combinados Inglés:   Cytochrome P-450 CYP3A/antagonists & inhibitors use Cytochrome P-450 CYP3A Inhibitors
 
Nota Histórica Inglés:   2006(1980) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   50572 
Identificador Único:   D051544 

Ocurrencia en la BVS: 		 

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